Trisha and David Kielb's baby is born, but soon afterwards the heart stops, turning their joy into fear; a woman experiences excruciating headaches.

A woman has shortness of breath, chest and joint pain, extreme fatigue, and a cough; strange symptoms appear in an energetic kindergartener.

A baby boy has bouts of vomiting and diarrhea from the day of his birth; a young woman experiences blackouts after she hits puberty.

A young college student named Mary Ann Piazza is misdiagnosed with pneumonia, but her cough keeps worsening accompanied with extreme fatigue.

A husband is rendered helpless by back pain. An overweight girl experiences dizziness and shortness of breath with any physical exertion.

Lavelle Fernandez and Roddy Palma's baby girl inexplicably turns blue 30 minutes after her birth; Laurie Scott suffers from excruciating headaches that won't go away.

A man who recently underwent an operation begins to suffer from swollen legs, insomnia, and sudden attacks of vomiting; a father discovers a strange lump on his tailbone.

When Heather and Toddy bring their baby home from the hospital, a strange rash soon appears on the baby's skin and it begins to suffer frequent fevers.

Doctors can't pinpoint the cause of the array of debilitating ailments a woman has been suffering from for more than 50 years.

Amanda Coveler, a woman who successfully gives birth to a second daughter after two miscarriages, faces challenges after giving birth.