Every season of Mystery Diagnosis ever, ranked from best to worst by thousands of votes from fans of the show. The best seasons of Mystery Diagnosis!

Grasping for Straws

Like Mother, Like Son

Not A Normal Newborn

Isaac's Nightmare

Why Is Emily Screaming?

Blood & Fire

Desperate for a Cure

Blood Brothers

A Puff of Smoke

An Unquenchable Thirst

Lethal Diet

Falling Through the Cracks

Eaten Alive

The Man Who Never Sweats

Fatal Secret

The Stabbing Sensation

The Man With Rocks in His Chest

Sleeping Beauty

The Man Who Turned Orange

Deadly Sore Throat

The 13 Year Stomach Ache

The Bearded Lady

The Boy Who Couldn't Breathe

Frenetic Genetics

The Baby Who Changed Colors

The Girl Who Couldn't Eat

Bizarre Visions

The Woman Who Craved Pickles

Donor Disaster

The Purple Puzzle

A Case of Paralysis

The Girl Who Couldn't Be Touched

The Girl Who Gagged

The Woman Who Kept Falling Down

A Deadly Cough

The Girl Nobody Believed

The Headache That Wouldn't Go Away

The Sickest Patient in the Hospital

Terrifying Tumours

The Woman Who Couldn't Cry

The Woman With a Knife in Her Head

The Woman With the Giant Lump

The Woman Who Couldn't Stop Rocking

The Baby Who Wouldn't Stop Crying

The Girl Who Couldn't Wake Up

The Girl Who Couldn't Move

The Boy Who Kept Swelling

The Boy Who Stopped Walking

The Boy Who Bit Himself

The Boy Who Could Break

The Black and Blue Baby

The Baby Who Couldn't Stop Eating

The Girl Who Fell Apart

The Girl Who Fell to Pieces

The Breasts That Changed Color

The Woman Who Saw Pink

The Girl With Holes in Her Jaw

The Woman Who Went Crazy

The Woman Who Couldn't Stop Burping

The Boy Who Never Cried

The Girl With Half a Face

The Girl Who Stopped Growing

The Woman Whose Legs Turned Black

The Man Who Tripled in Size

The Boy Who Couldn't Stop Eating

The Girl Whose Skin Came Off

The Girl Who Was Covered in Bumps

The Baby Who Smelled Like Pancakes

The Woman Whose Flesh Was Eaten Alive

The Boy Who Only Hopped

The Man With Hundreds of Lumps

The Baby Who Bruised Easily

The Girl With No Bowel

The Man Covered in Boils

The Toddler That Went Through Puberty

The Toddler That Stopped Walking

The Woman With Unusual DNA

The Boy With the 150lb Leg

Fight to the Last Breath

Trapped Inside Their Bodies

Dangerous Growths

When the Body Shuts Down

A Family's Desperate Search

Time is Running Out

Too Young To Be Sick

A Search for Answers

Stolen Senses

Simple Symptoms Turn Threatening

Mystery Diagnosis is a television program that airs on the OWN: Oprah Winfrey Network. Each episode focuses on two or more individuals and their struggles to find out what ailments they suffer from. As the program's title suggests, doctors have a difficult time finding a diagnosis, often due to nonspecific symptoms, the rarity of the condition or disease, or the patient's case being an unusual manifestation of said condition or disease.

The series debuted on Discovery Health Channel in 2005, and was continued when the Oprah Winfrey Network replaced Discovery Health on January 1, 2011; the current season premiered January 5, 2011.

The Best Seasons of Mystery Diagnosis

The Best Seasons of Mystery Diagnosis

Season 5

Season 3

Season 10

Other Seasons

Season 2

Season 9

Season 6

Season 8

Season 1

Season 7

Season 4