After experiencing a rough slide, Rembrandt and Maggie see Colin is nowhere to be found. More disturbing, they meet a stranger claiming he is Quinn Mallory. Rembrandt and Maggie learn too late that this is all apart of an evil genius' desperate plan to save his life.

Diana tries using a university lab to find a way to separate Quinn and Mallory, which leads to her first encounter with her double, a struggling single mother. Meanwhile, Mallory experiences violent flashbacks from Quinn's life.

The Sliders arrive on a world where Prohibition still exists, only it was caffeine that was outlawed. They meet a nightclub owner whose lover was murdered by a gang dealing in bootleg coffee.

The Sliders arrive on a world where combustion engines were outlawed by the government due to pollution. But a biker gang is fighting to keep their engines and Mallory falls for the gang's sexy leader.

A creature embeds a parasite in Maggie just before the slide, which takes the Sliders to a world where young adults are used in a mandatory organ-donor program. The others will have to find Maggie before she finds the perfect mate and lays her eggs.

While on vacation, Quinn and Rembrandt get mixed up in an illegal snake deal and find themselves stuck in the middle of no where surrounded by deadly snakes. Meanwhile, Wade and Maggie get involved with a shady man in their search for the others.

The Sliders track Rickman to a world where a mad scientist has been experimenting with genetic testing and has created a race of human hybrids.

Just before sliding out and escaping a small army, Mallory is shot with a laser beam and paralyzed. His only chance of walking again lies in a group of spiritual healers, but their cure could be much worse than being paralyzed.

On a world where tabloid journalism is in place of real news, a photo suggests Maggie is having an affair with the President. But the President's advisers decide to exploit it in order to distract attention from a war with Switzerland.

The timer continues to malfunction, giving the Sliders rougher slides than usual. To fix it, the Sliders need to get ahold of a gem, even if it means stealing.

The Sliders arrive in what is literally the happiest place on Earth. But in this small community, a little girl witnessed her grandfather leap into a mysterious chasm and begins to feel an overwhelming sorrow. Worse yet, it soon spreads to Rembrandt and Maggie.

Wade witnesses a murder just before the slide, but as the Sliders land on the next world, the same murder is about to occur. This time, Wade intervenes and this gets the Sliders involved with a disgraced federal judge and a United States under martial law.

The Sliders land on a world where San Francisco is a national park dedicated to the preservation of dinosaurs, which is home to a deadly Allosaurus. A bad fall causes Arturo to injure himself and lose the timer. Quinn goes out alone to search for it, while the others hide out from the Allosaurus in a cave.

The Sliders arrive on a world where electric tornadoes have almost completely wiped out the population. They find a secluded village somehow protected from the tornadoes and a dictator that may prevent the team from ever sliding again.

On a world where the American government is a monarchy, Rembrandt is mistaken for his double and discovers that he is about to be a father of royalty. The only problem is, on this world, it's the men who give birth to children.

Wade and Rembrandt recall their slide to a world plagued by earthquakes and populated by primitive people. Wade falls into a deep chasm and Quinn goes to rescue her, while Rembrandt learns of Arturo's illness.

The Sliders track Rickman to a superstitious town. Their search is further complicated when Quinn and Maggie are captured by natives living in a mysterious fog. There, Quinn runs into someone from his past--himself.

The Sliders' chase for Rickman takes them back to the world they helped colonize, the New World. Only they find that the colonists are being hunted by a hungry Tyrannosaurus Rex.

Wade falls under the spell of a rock band's charismatic lead singer, who is really a vampire and looking to use Wade to get the timer. Meanwhile, the others try to track down Rickman.

The Sliders arrive on a small island, with a very sick Maggie in tow. While looking for help, Rembrandt, Mallory and Diana meet the monks of a secluded monastery. Reluctantly, the monks allow them to stay and give Maggie medical attention. But the Sliders soon learn the monks have a secret and won't allow them to leave.

After trying to buy a candy bar, Maggie is kidnapped by a corporate conglomerate that uses data codes to control commerce.

The Sliders arrive on a world where Maggie's double was a heroic astronaut and loved by the public. When she is mistaken for her double, the public gets excited. After being kidnapped by the mysterious Leader, Maggie is taken by the government where she must confront her father.

The Sliders arrive at a mental institution in the middle of an unusual riot. Rembrandt and Maggie escape capture, but Diana and Mallory get left behind. While Mallory has managed to pose as a doctor, Diana is mistaken for a patient and undergoes the process of her brain being remapped.

A malfunctioning timer deposits the Sliders underwater in the Pacific Ocean. A merchant ship picks them up, but is taking them out of their sliding radius and decreasing the likelihood of a safe slide. Their only chance is to join up with a pirate crew to get back to California.

The Sliders confront Dr. Geiger again, in a collapsing dimension full of innocent victims.