After driving to Vegas to get married, Penny struggles with Leonard’s confession that he kissed another girl. Also, Sheldon doesn't know how to act after Amy pushes pause on their relationship.

Leonard isn’t thrilled when Penny considers taking a new job offered by her ex-boyfriend, Zack.

Raj and Howard's feud continues as the gang plan Halley's first birthday party. Sheldon's surprise for Amy's birthday goes awry when they get food poisoning. Also, Leonard gets a Christmas letter from his brother that causes him to spiral out about his own lack of accomplishments.

Raj finds himself in the middle of domestic drama when he learns the woman he's dating, has a very upset husband. Also, when Sheldon rents his old room back for a quiet place to work, he drives Leonard crazy by being a model tenant.

Leonard jumps through hoops to help secure the perfect wedding venue for Sheldon and Amy. Also, Bernadette and Howard have a hard time deciding who should stay at home with the kids and who should go back to work.

When Amy doesn’t have time to work on super-asymmetry, Sheldon goes to great lengths to ensure she’s available to work with him even it if means accidentally sabotaging her career in the process. Raj doesn’t want Howard to join him in hosting a show at the planetarium.

When Raj is asked to create a message in case a NASA mission discovers alien life, the guys fight over what he should do. Also, Penny is torn between auditioning for a movie or keeping her successful pharmaceutical sales job.

When Penny feels that Leonard is taking her for granted, she decides to go on a spa weekend with Amy. Also, Wolowitz and Koothrappali try to fix a squeaky floorboard in the baby’s room.

Leonard angers the university – and the entire physics community – after he gives an embarrassing interview. Also, Amy and Bernadette bond over having to hide their success from Sheldon and Howard.

Sheldon and Amy struggle with picking a wedding date, which stresses out Sheldon and causes him talking in his sleep. Meanwhile, Raj and Stuart fight over the attention of one of Bernadette's co-workers.

As Howard worries about fatherhood, he and Sheldon bond when they jointly assemble a model rocket. Meanwhile, Penny bonds with Leonard's mother, Beverly, much to his concern.

Sheldon and Amy try to eliminate stress from wedding planning by applying math to the process. Also, Raj “breaks up” with Howard after realizing his best friend is actually hurting his confidence.

When Bernadette won't go into labor, the gang tries different tactics to get things started. Also, Howard confronts Bernadette after Amy accidentally reveals she's already chosen their son's name.

Sheldon goes to Vegas to win money for science. Also, Penny and Bernadette take Amy wedding dress shopping, but her terrible choice entangles them in a web of lies.

Leonard and Amy make an unexpected trip to Arizona to fetch Sheldon; Penny interviews for a job at Bernadette's company; Stuart's relationship with Mrs. Wolowitz disturbs Howard.

Raj's honesty comes back to haunt him when his new girlfriend is unfriendly to Penny. The guys think about becoming part owners in Stuart's store.

While Sheldon says a tearful goodbye to the final installment of "Fun with Flags", Leonard, Howard and Raj search for something significant in a dead professor's research. And Bernadette finds out what her colleagues really think of her.

Friction ensues when a magazine fails to mention Leonard in an article about the paper he co-wrote with Sheldon. Also, a blackout at Mrs. Wolowitz’s home leads to a final family dinner in her honor.

Howard questions his engineering abilities when he and Sheldon can’t get a toy drone to fly. Meanwhile, a cancelled flight nearly prevents Leonard from giving the commencement address at his former high school, and Raj pits his parents against each other when his father cuts him off financially.

Sheldon and Raj confide in Bernadette when they can't handle Amy and Howard working together on a science project. Also, Penny and Leonard learn new tactics for how to deal with Sheldon from an unlikely source.

Leonard and Howard are furious after they learn Sheldon went to work with the military behind their backs. Also, while Bernadette is on bed rest, she asks Raj to do some digging when she suspects that Ruchi might be trying to take over her projects at work.

Sheldon and Amy try to pick their Best-Man and Maid of Honor by experimenting on the gang.

When Sheldon kicks Amy out to work solo, she and Leonard bond during a series of science experiments. Also, Bert the geologist replaces Wolowitz in the band Footprints on the Moon, and Sheldon finds Penny a surprising source of scientific inspiration.

Bill Gates visits Penny's work, and the gang schemes to meet him. Hilarity ensues. Meanwhile, Sheldon is convinced that he's a target of an April's Fools prank.

When Leonard learns Sheldon is the president of the tenants association, he decides to run against him. Also, Bernadette encourages Howard and Raj to find the owner of a drone after they find it in the backyard.