Liam continues taking Rocusin, and even steals a prescription from one of Grace's patients. After giving wrong medication to another patient, Liam blames Grace and convinces the patient to back up his story. Julia takes Liam's side in the matter. It takes Alice to recognize that it is Liam that is at fault and she goes to Lorcan about his behaviour. After being confronted, Liam admits to his drug abuse and it leaves Julia with no option but to suspend him from work. Elsewhere, Aideen doesn't turn up at the airport and later tells Dan to leave her alone. Later Dan is ...

Grace tells Ruairi about her missing sister Jasmine when he finds one of her flyer's on the photocopier. Lorcan asks Dr Kent about getting involved with someone given his HIV status. Keelin notices that a young client's fitness levels have gone through the roof and later he suffers a heart attack brought on by his use of illegal steroids. Ian and Liam agree a truce but Liam's dependence on Rocusin tablets makes him jump to incorrect conclusions about Ian later after he sees Ian's old buddies Phil and Martin outside their house.

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Brendan takes his grandmother home from hospital after she confesses that she knows she is dying, but wants to do so in her own bed.

Things are hotting up as affairs start rising to the surface. Paul tells Keelin he knows about her and Ed and begs her not to say anything to Yvonne about his carry on at the stag party. Meanwhile, Cathy tells Ed she might be pregnant and in turn Ed tells Keelin the news, who lets a congratulations slip to Cathy! Meanwhile, Yvonne hears Keelin and Paul fighting about his stag night antics and loses her temper with Keelin and tells her she doesn't want her to be her bridesmaid any more.

Daisy has fallen hook, line and sinker for Will, along with his drinking, drugs and fast living. They spend the night together in Cathy's flat. Will refuses to get up and come to work the next day, much to Daisy's dismay.

Dan is terrified when he realises he could be caught out for dating both Cathy and Sinéad and tries to find a way to prevent them meeting. Dan is thwarted when Sinéad meets Cathy. He tries to talk his way out of it by telling Cathy it was her idea to have a no strings attached relationship and as soon as they started to get serious he finished with Sinéad.

Alex is shaken when he bumps into an old friend at a club, who calls him Chris. Alex tells the guy to get lost claiming he doesn't know who he is and walks off with Sam in tow. Alex and Sam argue later at home. Sam thinks Alex has been picking up other men calling himself by a different name.

St. Matthew's Hospital Director Michael Kinsella is keen for Julia to take over the job but she declines and tells him she is happy at the Clarence Street Clinic but will she regret her decision when long standing patient of hers Elayne Sheridan discovers she is pregnant for the fourth time and places Julia in an unenviable dilemma. Meanwhiile, Dan continues his thirst for revenge on Niall Boylan through his wife, Aideen and discovers her love of art. Clodagh agrees to help out on the night clinic and the methadone bus and is moved by Lorcan's dedication to his ...

Clodagh, the new GP, has a bad start to her day when she knocks Ed over. Her day goes from bad to worse when she suspects a patient has an ectopic pregnancy, but is overruled by Cathy's father, Mr O'Callaghan.

Patrick is lonely and everything around him is further illustrating how alone he is. Through a chance encounter with an old acquaintance, he learns that his ex-wife Lisa is in town. They arrange to meet. Lisa hasn't seen him sober in a long time and is surprised by this new man. They get on great, the sparks are flying and their relationship takes a new turn.

Clodagh gets some shocking news, her father had an affair and she was the product of it. Daisy takes a fancy to Brendan's replacement, Will Cafferty. Cathy & Dan's relationship develops further.

Keelin has to decide if her business is worth losing her friends. Paul turns up at the Clinic asking Keelin to build bridges with a pregnant Kathleen, she is sceptical at first but is delighted when she arranges dinner with Kathleen. Keelin is furious to learn that Cathy has been referring patients to other physiotherapists.

Mr O'Callaghan's demise is revealed as he plummets from the high of the nomination for his Presidency to the depths of despair when he loses out. He is unable to take any more or to reach out to anybody, most notably Cathy

Richard is struggling to deal with his wife Annie's illness while trying to keep his home and work life separate. His daughter Flossie is devastated when she discovers that she could have the Huntington's gene. Trying to pretend that everything is okay and not accepting help has not worked, Richard finally comes to the realisation that he has to face up to his wife's illness.

Patrick refuses to take an agitated Conor for a session after Conor is rude and insults Bernie. Clodagh has had enough with her acupuncture patients and tells Julia she would like to concentrate on her general practice. Daisy is clearly uncomfortable around Jack and calls him a creep under her breath. Cathy is puzzled by the way Dan is acting and agrees to meet him for lunch. Liam teaches his son, Ian, a lesson after he had a few beers and fell over drunk. Ann Marie teases Jack about Clodagh fancying him but Jack tells her she has nothing to worry about.

Cathy continues to lie in a coma after being run over by Niall Boylan unaware that she lost her cherished baby girl - Rachel - in the accident. Liam's son Ian is in trouble yet again and gets expelled from school and Liam has no choice but to put him into a fee paying school. Daisy returns home with Conor to be at Cathy's bedside and is there when Cathy suffers a brain haemorrhage and dies.

Alice secures a temporary role as the nurse in the clinic, and is keen to celebrate with Dan. Annie Ward brings her ex-boyfriend, Dave, to the night clinic in an effort to wean him off heroin with disastrous consequences.

Cathy wakes up to see Dan in the next room and wonders what happened the night before. Ed meanwhile wakes up at Patrick's who tells him that he should go home. Dan sees a former patient of Ed's for a cosmetic consultation and suspects she has a thyroid problem.

Dan and Daisy face Niall Boylan in court but later find out that he has been killed. After Alice lets slip about Lorcan's HIV status Dan confronts him. Later, Dan is arrested for Niall Boylan's murder.

Keelin has to face up to the news about her mother's cancer. She realises that her family cannot cope and she has to give up her single lifestyle and move back home to care for Mary, a difficult woman whom Keelin has never got on with at the best of times. Fiona goes further off the rails, and Cathy is forced to dismiss her.

Susie's life is changed totally with the unexpected arrival of her teenage daughter Moya, who has decided to leave her home with Susie's parents and move in with her mother.

Patrick's long-running case with Seán, plus his constant work load, takes its toll on his own mental health. In addition he has to face Seán's father who resents the disruption caused to his family life by the disclosure of the secret. The usually calm Patrick shocks everyone by his behaviour.

Dermot asks Fiona to join him for lunch. Cathy is interested in buying next door and goes to her Dad in the hope of interesting him in investing.

Dan's grief over Cathy's death is overshadowed by hearing that Niall Boylan will escape relatively free from a serious conviction. Dan's solicitor warns Dan to stay away from Niall. Meanwhile, new locum Dr Grace Sefate makes an impact on her first day when her belongings turn up before her. This unusual entrance immediately gives Grace an air of intrigue but she immediately asserts herself as a capable and dedicated doctor. Lorcan starts to struggle with his illness, now that he is on a harsh course of anti-retroviral medication for his HIV and this sees him becoming ...