As the doctors consider their futures, they work together to solve one of the most important cases of their careers.

Dr. Shaun Murphy seeks legal representation to help him win a case and puts his faith in a promising, young lawyer who has obsessive compulsive disorder.

The team at St. Bonaventure needs to quickly discover the truth behind a young college student’s unexplained injuries before his condition worsens. Meanwhile, after losing his most prized possession, Shaun’s distraction during a surgical procedure may end up risking more than just his job.

Shaun and Lea happen upon a terrible car accident and discover a young pregnant mother who has been badly injured and needs immediate medical attention. Dr. Glassman is apprehensive when a figure from his past reaches out for help.

The staff of St. Bonaventure Hospital works against time and their own personal safety to save the lives of those around them.

The team must deal with a mass casualty event that forces them to put aside their emotions following a recent tragedy.

Dr. Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join the prestigious St. Bonaventure hospital’s surgical unit. Alone in the world and unable to personally connect with those around him, his only advocate, Dr. Aaron Glassman, challenges the skepticism and prejudices of the hospital’s board and staff when he brings him in to join the team. Shaun will need to work harder than he ever has before, as he navigates his new environment and relationships to prove to his colleagues that his extraordinary medical gifts will save lives.

Shaun visits his father on his deathbed and the family reunion reveals unexpected results. Melendez, Park, Reznick and Claire treat an injured star NFL player with severe spinal damage. Claire addresses her mental health.

The city of San Jose is rocked by a massive earthquake that puts the staff of St. Bonaventure Hospital on high alert as they race to assess the damage and account for the safety of their colleagues and friends. Meanwhile, Dr. Neil Melendez and Dr. Aaron Glassman are attending a charity event when their lives are threatened by the earthquake.

Dr. Claire Browne returns from her work in Guatemala for a personal medical examination. Elsewhere, Dr. Glassman struggles to manage Hannah, who remains unresponsive to his attempts to help. Park seeks out the perfect last-minute wedding location.

While in the exam area of St. Bonaventure Hospital, Dr. Shaun Murphy encounters a young patient who looks eerily similar to his deceased brother, Steve. After discovering his parents have hidden his diagnosis from him, Shaun struggles to understand why he doesn’t deserve to hear the truth about his own health. Meanwhile, the team can’t figure out what keeps triggering their patients’ increasingly severe allergic reactions and races to find the cause before the next one kills another patient.

Dr. Shaun Murphy and Dr. Claire Browne devise an experimental procedure that can save the leg and life of a young groom, that is if his bride-to-be and parents can learn to work together. Meanwhile, Jared struggles to emotionally connect with his patient whose scars may prove too deep to overcome.

Dr. Shaun Murphy has to confront prejudice from an unlikely source when he takes on the case of a patient with autism, and Dr. Jared Kalu has to learn to accept his limitations as a surgeon.

Dr. Claire Brown faces complications at home and work as she prepares to lead her first surgery. Meanwhile, a sports fishing accident challenges the rest of the staff as they look to treat the fisherman’s injuries without damaging his prize catch.

Dr. Shaun Murphy’s attention to detail complicates his first day at St. Bonaventure Hospital. Meanwhile, Dr. Claire Browne learns a valuable lesson about honesty when confronted with a difficult diagnosis for her patient.

During a robbery at the grocery mart Dr. Shaun Murphy is shopping at, his communication limitations puts lives at risk. Meanwhile, after Shaun's traumatic day, Dr. Aaron Glassman worries that he isn't doing enough to help Shaun.

Dr. Shaun Murphy is desperate to join the team on a dangerous procedure involving a patient’s tumor removal. However, having been removed from the surgery team by Dr. Jackson Han, Shaun must use his talents to help figure out the cause of an infant’s injuries.

Dr. Shaun Murphy must perform a risky surgery on a patient without electricity when the power suddenly goes out. Meanwhile Lim and Dr. Mateo Rendón Osma’s relationship deepens as they overcome difficulties during the surgery.

Shaun and Lea’s long-awaited wedding reception is interrupted by a violent attack at the hospital and the entire team must mobilize to save the victims. Meanwhile, the trauma of seeing people he cares for in life-threatening situations is affecting Shaun in more ways than one.

Shaun and Lea soon learn that their surprise pregnancy may also come with additional complications. Meanwhile, Doctors Park, Reznick and Allen treat a teen with Gardner’s syndrome whose past surgical history jeopardizes the outcome of his current one.

Shaun and Lea are heading to the delivery room and everyone from the hospital is also there, except for one very important person. Meanwhile, a tragic accident involving Drs. Perez and Kalu pulls everyone away, including Dr. Murphy.

A charming young doctor puts a member of the surgical team in an awkward position at work; Dr. Glassman suggests that Dr. Shaun Murphy meet with a therapist.

Dr. Shaun Murphy questions the need for an elective surgery that will allow his young patient to smile for the first time. Meanwhile, Dr. Claire Brown and Dr. Morgan Reznick discover that their patient lied about her identity.

Dr. Andrews tries to convince a grieving family to donate their teenage daughter’s face to another young girl whose face was horribly disfigured in an accident.

Shaun’s blunt honesty with a distraught mother of a critically ill newborn baby causes the new chief of Surgery to question keeping him on as a resident.