An abnormality on the ultrasound alarms parents expecting a baby; a biology teacher has a series of strange symptoms.

The Purple Puzzle

A Case of Paralysis

Donor Disaster

Doctors wonder why an apparently healthy baby fails to achieve its developmental goals; on the other hand, a woman who seemed to be in good health suddenly becomes ill.

The Girl Who Couldn't Eat

A woman experiences chronic stomach pain and diarrhea attributed to irritable bowel syndrome; another faces extreme fatigue and night sweating while pregnant.

Bizarre Visions

A baby boy could not keep any food down; an X-Ray revealed that he had been born with a diaphragmatic hernia. A woman who suffers from extreme fatigue has strange cravings for pickles; when her heart nearly stops, doctors try to find the cause of her problems.

The Woman Who Craved Pickles

A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

Mystery Diagnosis is a television program that airs on the OWN: Oprah Winfrey Network. Each episode focuses on two or more individuals and their struggles to find out what ailments they suffer from. As the program's title suggests, doctors have a difficult time finding a diagnosis, often due to nonspecific symptoms, the rarity of the condition or disease, or the patient's case being an unusual manifestation of said condition or disease.

The series debuted on Discovery Health Channel in 2005, and was continued when the Oprah Winfrey Network replaced Discovery Health on January 1, 2011; the current season premiered January 5, 2011.

The Purple Puzzle

Seasons10

Season 4 Episodes6

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Episode Summary