After hearing Bernie use inappropriate language at home, Bryana goes to school and repeats it—much to the horror of her teacher. Soon after, a social worker shows up at the house to discuss Bernie's hostility problems.

Bernie takes the family on a tour of his old stomping grounds. Vanessa attempts to find her mother.

After a Jewish family arrive in the neighborhood, Bernie urges Jordan to befriending the son, David. Though hesitant at first Jordan begins to develop a friendship with his new neighbor. Not long after-wards David invites Jordan to attend his cousin's bar mitzvahs with him. After receiving various expensive parting gifts Jordan and David decide to crash bar mitzvahs of people to whom they do not know in order to receive more gifts. Before long it's time for David's bar mitzvahs but Jordan comes to a dilemma because this happens to be the same day of a very wealthy boy's bar mitzvahs. So Jordan must beside between friendship or material possessions.

When Wanda plans a play date for a group of kids, Bernie ends up winning over the moms for the afternoon and becoming defensive about his masculinity.

when Bernie realizes that anything he says to Jordan and Bryana first goes through Vanessa, he decides to stop fighting the situation and let Vanessa be responsible for the kids.

In the pilot, much to his chagrin, Bernie and Wanda are forced to take care of his sister's three children, Vanessa, Jordan, and Bryanna since she can no longer take care of them anymore.

Bernie's desperate to get away to Vegas with his frineds, but Bryana's birthday and the germ infested children that it causes make it a difficulty.

Jordan is tormented by bullies at school, so Bernie teaches him some moves that unfortunately turn Jordan into a monster.

The kids get a dog from the pound, thinking it will be the perfect present for Bernie. Bernie finds the dog, hides it, thinking it is the perfect present for the kids. They think he took it back to the pound, so they try and get revenge.

Bernie becomes concerned when he begins to see the classic signs that old age is catching up with him. He's forgetful, has aches and pains, and is finding gray hairs in, uh, unwanted places. When a panic attack sends Bernie to the Emergency Room after an argument with the kids, he decides to not let the kids send him to an early grave. He fights back and begins trying to act young again. He blasts his music and nags his friends for not staying up all night to play poker with him. Bernie only makes matters worse however when all his ""young"" activities take their toll on his mind and body. When Bryana asks Bernie to play in her Father-Daughter Basketball tournament at school, he complains, saying that he is just too old to play. When he gets to the game though, he realizes that he should be playing and joins in. Although he gets hurt playing, Bernie realizes that being old doesn't mean stopping your life.

When Kelly's girlfriend throws him out, Bernie lets him stay at the house.

Bernie and Wanda attend Vanessa's parent night at her school. They are shocked to find that her teacher likes her, and thinks she is not being challenged enough, so he suggests she run for class president. Jordan is upset when he puts his time into making a dung beetle project, but ends up only getting the huge pile of dung done. So Bernie decides to help Jordan on his next project, which turns out to be a VERY detailed model of an old building, but Bernie does all the work. Vanessa also asks Bernie to help her on her campaign, so Bernie appears as many characters in her video of why she should be allected. It goes over so well that Vanessa asks Bernie to compete in the school talent show, to help along her campaign. Meanwhile, Jordan's project turns out great, but Bernie doesn't know that Jordan has decided to make a few extra things. He changes the roof, throws in some plastic people, and sets it on fire, laughing hysterically. Bernie trips on pieces of it, trying to put the fire out

The kids' carelessness causes Bernie to have a near-death experience.

Bernie and Wanda bring the kids to church to discipline them, but Bernie ends up being the immature one. Later on, the Bishop and Deacon show up at Bernie's house during his poker night and suggest that Bernie allow them to use his house for bible study.

On a hot day, Vanessa detours the family's trip to the water park. Back at home, the kids act wild and the air conditioning breaks.

Jordan sets his sights on joining Vanessa and Bryana on the Bernie Mac Hall of Fame awards shelf. He decides to join his school's football team after hearing that everyone on the squad gets a trophy just for participating. Bernie is thrilled that Jordan is playing football—until he sees his playing skills.

Bernie is booked on a popular morning radio show, and he gets himself into trouble with the whole family when he draws from his private life to bring comedy to the public airwaves.

When someone breaks into the Mac house, Bernie realizes how vulnerable his family is and turns the house into a high-security compound. Bernie is reminded by his friends of all the crime that happens outside of the home and drives his family crazy with his overprotectiveness.

Don Rickles plays a neighbor who dispenses some unorthodox advice when Bernie is told he has high cholesterol. Though it's a sore shoulder and badgering from Wanda that sends Bernie to the doctor, he comes away sore at the physician for weighing him down with bad news. The problem can be controlled through diet and exercise, but that would mean avoiding the finer things to which Mac is accustomed... like fries from Royal Burger. But neighborly Don Rickles suggests that stress is the real problem, and what causes stress? Why, dieting, of course! And that's the case Bernie presents to an incredulous Wanda.

Wesley Snipes takes a genial comic spin as Wanda's easygoing boss, Duke, who invites the couple to a dinner party. Feeling as if the kids are ""turning my brain into mush,"" Bernie relishes this rare opportunity for adult conversation. But playing a parlor game underscores just how much being around the kids has influenced Bernie — asked to name something that flies, he submits ""Tinkerbell"" — and he takes some, well, kidding, from the Duke. Back at home, Vanessa baby-sits her siblings and takes matters into her own hand when Jordan gets troublesome.

After taking the kids to the movies, Las Vegas-bound Bernie is further delayed by scenes that grow out of what they saw there, but weren't supposed to see.

When a litigious neighbor asks Bernie to tear down the treehouse he built for Jordan, it leads to an all-night standoff. Meanwhile, a relentless Bryanna tries to put a bumper sticker that represents her good grades in school on Wanda's car, but Wanda tries different ways to put the sticker anywhere but on her car.

Bernie and Wanda host a Mac family reunion barbecue for about 50 of Bernie's extended relatives who invade L.A. for the weekend. At first, Bernie is excited and looks forward to bonding with his relatives and strengthening their family ties, but when his Aunt Sis starts to pester him about co-hosting a cooking show with her on the Food Network, cousin Lou starts to harass him, and his older brother Carl questions the way he and Wanda are raising the children, Bernie starts to question why he agreed to host the reunion in the first place. Meanwhile, Vanessa and Shonte, a distant cousin by marriage, flirt with each other until Bernie informs them that they are more closely related than they thought.

After misbehaving yet again, Bernie punishes Bryana and Jordan severely. Yet again Wanda thinks he's being too hard on them. But in the end, she catches on. Vanessa turns out to be the sneakiest of them all.

Bryana's daddy Bryan helps out around the house and the kids start preferring him over their Uncle Bernie causing Bernie Mac to take offense. Baby Girl gets called flat-chested at school and Bryan and Bernie fight over who gets to buy her a new bra. Jordan competes for "best smile" at school.