The team considers if a father who cleans crime scenes for a living led to his disappearance with his daughter.

When a college student disappears after making racial remarks in a class, the team wonders if those may be directly connected to his disappearance.

The team Search for a missing motivational speaker only to find that there is an abundance of suspects,The find out that they man is no who he appears to be.

Jack and the team investigate when Sadik Marku's son goes missing along with the boy's mother, and Samantha worries that Jack is more interested in settling an old score with Marku than with finding the missing woman and boy.

The four-year-old adopted son of a celebrity couple is kidnapped, and the team must determine if the reason has to deal with the parents' status or the boy's own Sudanese origin.

The team searches for a missing mother who they believe may be searching for her son, who is also missing.

The disappearance of an ultimate fighter leads the team to investigate his background, where they learn the man had a number of enemies.

Maggie Cartwright appears to have simply walked away from every thing in her life, having left everything of hers behind. Later a ransom note appears on her mother's email list demanding a million dollars for her safe return.

Chet Collins has been searching for his son since the boy was kidnapped four years earlier on a camping trip, and is the one case that Jack has never been able to forget. When Chet disappears, leaving behind only his wedding ring and the mountains of debt he had accumulated in his search, Jack will go to any lengths to find Collins and save him from himself.

The team find themselves up against the ropes as multiple mysteries arise in the case of a boxer. Dante Jones disappears moments before a bout with a $500,000 purse that which could have made him a title contender. Jack suspects it's stunt, but Vivian, a Jones fan, can't believe that the charity-loving, straight-arrow fighter would go doewn that low road. The search goes in a new direction when his younger brother who he is always bailing out of trouble, vanishes. Then it's learned he has made 2 million dollers in the past five years,but he only has $6000 in his bank account.

The team investigates when Malia Norton, a teenager at a detention center, disappears after being threatened by one of the other residents. Malia had been involved in a drinking and driving accident that had seriously injured her sister's boyfriend and killed another young man. The investigation at the detention center uncovers a lot of secrets that some of the residents would prefer to keep well hidden.

The team investigates the disappearance of social worker Eric Hayes, who had given thirty days notice to his job not long before. When their investigation leads them to a young pregnant woman who had already lost one child to the system, the agents begin to believe the disillusioned social worker may have been having an affair but soon discover that he may have been trying to right the wrong that drove him from his job. Danny has trouble with the investigation, as it reminds him of his own experience in foster care. Jack confides in Samantha about his relationship with Ann, but it may be too late.

Vivian thinks about her recent surgical problems while searching for a missing woman with a terminal condition.

The team tries to determine whether or not the recent disappearance of an air traffic controller has connections to the Middle East. The team soon learns that his wife died in an automobile accident and he was having an affair with her sister.

A newly elected senator goes missing and Jack immediately turns his attention towards her husband.

When a young, interracial boy goes missing, race and money appear to play the starring roles in the investigation.

A former soldier, now stuntman, goes missing and the team learns that he changed his will only short time before he went missing which makes them wonder who needed the money.

A teenage girl disappears after joining a cult. In the office, Elena encounters problems with Carlos in their custody battle for Sofie.

When a woman disappears after her boyfriend is killed by the police, the team suspects gang involvement. Later, Sam learns she's pregnant.

An office shooting forces a woman to disappear, possibly to hide a deep secret.

Malone and his team start off the new year investigating how a private investigator might have went missing.

Jack goes missing after taking a case into his own hands which soon becomes intertwined with a human trafficking prostitution case that Vivian is working on.

The team searches for a paraplegic who had been injured two years earlier in a car accident and is now missing. Their investigation shocks them when they discover the truth in what may have caused his disappearance.

The team must decide whether or not a doctor's past is a factor in her disappearance.

The team is called in to investigate the custody kidnapping over a teen who vanished after last seen with her mother. But the case takes a turn when they discover the teen was living a secret life. Meanwhile, there is a bump in the road of the relationship between Jack and Samantha.