The team considers if a father who cleans crime scenes for a living led to his disappearance with his daughter.

When a college student disappears after making racial remarks in a class, the team wonders if those may be directly connected to his disappearance.

The team Search for a missing motivational speaker only to find that there is an abundance of suspects,The find out that they man is no who he appears to be.

Seven years ago, a thirteen-year-old girl named Amber Bryce went missing, and suspicion fell on her boyfriend, then-seventeen-year-old Curtis Horne. When Daisy Thorpe, who had become obsessed with getting justice for Amber's death, also ends up missing, the team is called in to investigate. While Martin and Danny work from the office, Sam and Jack work in the field, starting their investigation with the local cleric, Amber's father, and trying to find out why Curtis Horne has stayed in town all these years. While Vivian is home having troubles with Reggie, Martin makes a decision about his relationship with Sam.

Jack and the team investigate when Sadik Marku's son goes missing along with the boy's mother, and Samantha worries that Jack is more interested in settling an old score with Marku than with finding the missing woman and boy.

The four-year-old adopted son of a celebrity couple is kidnapped, and the team must determine if the reason has to deal with the parents' status or the boy's own Sudanese origin.

The team searches for a missing mother who they believe may be searching for her son, who is also missing.

The disappearance of an ultimate fighter leads the team to investigate his background, where they learn the man had a number of enemies.

This time, the team searches for a delusional appearing Sci-fi fanatic who disappeared from his appartment after ranting on about those ""out to get him"" (before peeling back the tinfoil covering his windows). Jack also has to deal with the consequences of his actions in the affair and how it affected the rest of the team.

To find a missing young mother who was recruited as a drug mule, Samantha goes undercover to lure the drug trafficker who recruited the young woman.

Things with Jack and Maria's divorce are getting nastier as Maria's attorney forces Jack to relive not only his childhood traumas, but also throw his affair with Sam in his face and attack his dedication to his job.

When Mac, a prisoner only two weeks from parole, disappears during a fight in the yard along with another prisoner, his sister contacts the FBI for help. No one can figure out why a member of the Aryan gang would escape with a black prisoner. While Martin and Viv talk to the other prisoners and Jack tries to wade his way through the sister's lies and half-truths where her brother is concerned, Danny focuses on a new prisoner who Mac had been protecting.

Martin is swamped with guilt after a young boy is kidnapped shortly after he jogs by. The team tries to reassure Martin that his presence was a help rather than a hindrance as they search for the kidnapped child, but Sam's continued reluctance to admit to their relationship partnered with Martin's jealousy of her relationship with Jack only cause more problems.

Paige was last seen sneaking out of her office at the same time as an NYPD detective was asking her boss to direct him to Paige for a routine inquiry. To the team's surprise, the NYPD detective turns out to have been an imposter, causing them to question why Paige chose to run from this mystery man, what he wanted -- and if he caught up with her. Further investigation uncovers that the seemingly upstanding and socially conscious Paige was involved in a lucrative identity theft ring with close ties to a terrorist on a watch list who was recently seen in New York with her. Meanwhile, the remaining team members are gravely concerned about Vivian, who is undergoing open-heart surgery on that very day.

The team investigates when Malia Norton, a teenager at a detention center, disappears after being threatened by one of the other residents. Malia had been involved in a drinking and driving accident that had seriously injured her sister's boyfriend and killed another young man. The investigation at the detention center uncovers a lot of secrets that some of the residents would prefer to keep well hidden.

The team investigates the disappearance of social worker Eric Hayes, who had given thirty days notice to his job not long before. When their investigation leads them to a young pregnant woman who had already lost one child to the system, the agents begin to believe the disillusioned social worker may have been having an affair but soon discover that he may have been trying to right the wrong that drove him from his job. Danny has trouble with the investigation, as it reminds him of his own experience in foster care. Jack confides in Samantha about his relationship with Ann, but it may be too late.

Vivian thinks about her recent surgical problems while searching for a missing woman with a terminal condition.

The team tries to determine whether or not the recent disappearance of an air traffic controller has connections to the Middle East. The team soon learns that his wife died in an automobile accident and he was having an affair with her sister.

A newly elected senator goes missing and Jack immediately turns his attention towards her husband.

When a young, interracial boy goes missing, race and money appear to play the starring roles in the investigation.

A former soldier, now stuntman, goes missing and the team learns that he changed his will only short time before he went missing which makes them wonder who needed the money.

A teenage girl disappears after joining a cult. In the office, Elena encounters problems with Carlos in their custody battle for Sofie.

When a woman disappears after her boyfriend is killed by the police, the team suspects gang involvement. Later, Sam learns she's pregnant.

An office shooting forces a woman to disappear, possibly to hide a deep secret.

Malone and his team start off the new year investigating how a private investigator might have went missing.