A young boy, Jeffrey, dies when he falls from a building, after being chased in there. After the autopsy a doctor turns up wanting to have the brain. Jeffrey had Tourette's Syndrome and the doctor wants to try and find out what causes it and how to cure it. This is the only way he can research it as the drug companies don't think they could make enough money to make it worth their while.

Three deaths due to food poisoning are linked to a football stadium where a big championship game is due to take place. Quincy has three days to find the source before 90,000 spectators come to watch and are put in jeopardy.

A rushed autopsy by Dr. Asten places Quincy in a difficult position as he tries to clear his bosses' name.

Two customs officers want Quincy's help in catching arresting a diamond smuggling ring. A courier they were following was killed when a bus at the airport and, as Quincy is going to a Las Vegas to judge a Miss Coroner Contest; they want him to take the couriers place. He has to deliver the diamonds to a known mobster, something he really, really does not want to do!

Quincy is hired as a technical director for a movie that is recreating a famous homicide case. Watching the murder scene being filmed convinces him that the real murderer is still loose and that the woman in jail for the crime was innocent. He sets out to find the truth but is hampered by the reluctance of the woman convicted to get involved. She only has a few months now until her parole hearing and if she is still trying to prove her innocence she has no chance of getting out if Quincy fails to find the real killer.

When Quincy sits on a jury for a homicide case he realizes that there are errors in the evidence, which could lead to the conviction of an innocent man. Not being one to sit by without doing anything he is soon causing uproar in the court with his constant questioning and interrupting.

A doctor persuades a couple that their new baby, which was born with Down's syndrome, will not have any life outside of hospitals and institutions. The child is then allowed to starve to death, something that causes a second doctor to ask for the original one to be charged with murder. Quincy investigates and finds out more about how children with Down's syndrome are treated in the world. To do this he visits a family that look after six children on their own.

Quincy is going to be testifying in the appeal of a big mob boss, Victor Ramsay, and his evidence is vital to him staying in prison. Ramsay and his people have other ideas though and have a plan to guarantee his release. They kill the only witness and then set about making sure that Quincy is discredited. Once this is done Quincy and the D.A. have three weeks to come up with more evidence or Victor Ramsay will be released.

A suspected rapist seeks revenge on Quincy by attacking his friend

While working late at the lab Quincy and Sam are taken hostage by syndicate chief Vincent DiNardi. He has been poisoned and wants the two medical examiners to find out how the toxin was administered. Once he knows that he can make sure arrangements are completed for his revenge before he dies.

Finally getting to spend a bit of leave time with his latest flame, Barbara, Quincy heads off away from Los Angeles. They nearly get run off the road and then witness an accident. Quincy then finds himself in a life or death race to isolate a mysterious poison, found in the woman's body, that has already claimed two lives

A fire in a small motel room causes the death of the single woman occupying it. The evidence shows that the identity of the woman is Jessica Ross, the country's top newswoman. As Quincy begins a press conference confirming her death Jessica walks in through the door, declaring that the rumours of her death are unfounded. Quincy and Asten are shocked but soon Quincy doesn't believe that this woman is Ross, and that his original findings were correct. He thinks that the body was Jessica ross and this woman is an imposter.

Quincy's latest ladyfriend moves into a new apartment and accidentally discovers two mummified bodies. He finds himself up against a group of oddball residents when he tries to find out what is going on, who the bodies belong to and where they came from.

Quincy delves into the world of cosmetic surgery after he autopsies a woman who killed herself because she hated the scars a botched operation caused. He discovers that the plastic surgeon isn't in fact a qualified plastic surgeon, only a qualified MD. The law allows anyone who has qualified as a doctor to call himself any kind of specialist he likes.

Quincy has to autopsy a man who died at the county hospital. He is amazed at the ability of the Dr. who tried to save him. It turns out though that the patient was originally taken to a different hospital that turned the ambulance away because the man did not have any insurance. Quincy visits the hospital and, after seeing the same thing happen again, decides to make sure that the owner, Dr. Rollins, does not get to buy another local hospital and run it the same way.

On his way to a Forensic Pathologist convention in Sacramento, the Sheriff of a small town stops Quincy on the road. He was trying to stay awake by sticking his head out of the window. The Sheriff decides to put Quincy in jail for his own good. That night a fire starts in the cells and four men die. The towns' authorities call all the deaths accidental but Quincy, doing some of the autopsies to help the local Dr. is convinced that one of the victims was murdered.

Two old Korean war buddies of Quincy's, Charlie and Max, have an accident in one of the planes owned by their company. Although the most badly injured of the two should have survived for some reason he dies in hospital. The police think that Charlie could have killed his partner because of another, bigger, company wanting to buy up theirs and Quincy sets out to prove that he would not have done such a thing to his best friend and partner.

Polly Carmody, a young 9 year old girl, is murdered and found in a refuse bin. The police quickly pick up a suspect but Lt. Alex Markasian thinks that he doesn't fit the profile of a child murderer. He is much more interested in the fact that the 'father' of Polly is in fact her stepfather, and has only been in the house for a couple of months. When the arrested suspects blood type doesn't match the blood found on the victioms clothing Donald Thompson, the stepfather, becomes an even more likely suspect. This is made even more likely when Alex and Quincy discover some disturbing things in Thompsons' background.

A German shepherd, bought as a family pet, savages and kills a young girl. Quincy investigates and finds out that there are absolutely no rules or regulations regarding dog trainers. He decides that he wants to do something about this but soon realizes that not only is this near impossible but that there is also more to this particular situation then it first seemed.

Quincy, Lee and Danny are all in Lake Tahoe together. Quincy is there for a forensic Pathologist convention and the others for a weekend break. While they are there the guests and staff start coming down with some kind of strange illness. Quincy and a couple of other Forensic Pathologists are called in to help but when some of the patients start dying they still have no clue as to what is killing them. To make things worse the casino owner does not want to admit that anything is wrong, as it will affect his bookings and profits.

The disease continues to spread and the rest of the hotel/casino's guests want to know what is going on. They want to get out of the building but Quincy and his colleagues know that they have to keep the disease, and the guests, contained. If the disease gets out of the hotel it could cause an epidemic that could quickly spread all over the country!

A thigh bone is found buried on the building site of a new student union building. Quincy is teaching a class at the university and soon involves himself and his students who the bone belonged to, how they died and possibly even who killed him. Not surprisingly Monaghan and Asten consider this a complete waste of time and want Quincy to get back to his job and stop bothering them.

Quincy and Danny go on a fishing holiday to the beautiful lakeside town of Paradise, free from their troubles of restaurant managing and Dr. Asten. Almost as soon as they have started fishing a young woman pulls her boat alongside them and thanks Quincy for coming to investigate her mother's murder! Quincy has no idea what she is on about but is affected by her pleading and agrees to look into it.

At 4 am one morning Quincy is awoken by the arrival of a man at his boat. He is in a very bad shape and he dies before Quincy can do anything to save him. He takes him to the morgue and does an autopsy on him. The next morning Quincy is surprised to find that his results and slides have not turned up. When he goes to find out why he finds out that they are not all that is missing, so is the body! Without any proof of a body everyone thinks that he must have been mistaken, especially when Monaghan visits the man's workplace and finds him there!

A young woman dies in a bar, apparently of a heart attack. After the autopsy Quincy is sure that something is not quite as it seems and soon discovers some unsettling facts about her husband.