The Queen Bees of medicine are back with a vengeance. Friendships have been broken as Quad discovers long-time BFF Mariah has been talking behind her back. Meanwhile, Dr. Jackie shocks Dr. Simone with news that she wants a baby. Later, at Dr. Heavenly’s cocktail party, sparks fly as Toya accuses Dr. Simone of inappropriate behavior with Toya's husband.

Jackie's date night with Curtis takes a surprising turn when she tells him about her plan to have a child. Meanwhile, Mariah talks her balding hubby into getting hair transplant surgery. After the showdown at Dr. Heavenly's, Toya and Dr. Simone meet to hash out their issues, but end up embroiled in even bigger conflict.

A peace summit between Quad and Mariah turns into explosive confrontation that quickly spreads across the medical community. Dr. Jackie meets with Dr. Heavenly to hash out their issues, but realizes it’s not exactly the resolution she was hoping for. Meanwhile, Toya hosts a birthday party for her son; its all fun and games until Quad and Mariah’s feud becomes the talk of the party.

As Mariah continues to deal with the fallout from her fight with Quad, Quad turns her focus to developing her puppy fashion line. Dr. Simone and Cecil's financial problems start to weigh heavily on their marriage. With Cecil away, Dr. Simone hosts a fun filled slumber party where she learns how to get her sexy back. Meanwhile, Lisa Nicole receives some devastating news that could turn her world upside down.

Quad hires a new designer to help launch her puppy clothing line. Tensions flare at Lisa Nicole's speaking event when Toya confronts Dr. Simone on her bad behavior. The fighting continues to spiral out of control as Quad and Mariah come face to face in an explosive showdown.

The drama of the WEN Conference continues with more tears and accusations thrown out by Mariah and Quad. It's the big day for Lisa as she finally finds out whether or not she's cancer free. In a last ditch effort to save their friendship, Quad invites Mariah to an upcoming fashion show.

Dr. Simone finally reveals her financial issues to a shocked and speechless Dr. Jackie. Meanwhile, Dr. Heavenly hears some startling information about Mariah. An explosion erupts at the Women of Atlanta fashion show when Reco Chapple and Mariah finally come face to face.

When Heavenly invites the ladies over for a dinner party, long-standing alliances are shattered as the ladies deal with the aftermath of Mariah and Quad's catwalk cat fight and are forced to choose sides.

Quad and Reco scramble to finish their puppy couture samples before their investor meeting, but Mariah files a restraining order against Reco that threatens their progress. Lisa Nicole throws a fantastical princess party for her daughter, but tempers flare as Simone disinvites Mariah from the couple's trip

Simone enlists Jackie's help in a scheme to resuscitate her flatlining love life. While Simone springs a romantic surprise on Cecil, Jackie's babysitting skills are pushed to the limit when Simone's kids wreak havoc on the house . Meanwhile, Quad's business venture leads to a heated argument with her husband that threatens their relationship. Toya and Eugene encounter an unexpected financial problem.

As the group's long awaited couples retreat approaches, Simone encourages Mariah to make a surprise visit. The couples arrive in the Blue Ridge Mountains, eager for a break from the constant drama of Atlanta's medical circle. Greg makes a controversial statement that upsets several of the wives, and a conversation about adultery leads to a shocking revelation about Darren and Lisa's relationship.

The ladies' mission to have a peaceful trip proves to be impossible when their drama follows them to Blue Ridge. Tempers flare once Quad learns that Simone secretly invited Mariah along. Mariah decides to embrace the outdoors and leaves her mark on the wilderness. Later an intense relationship exercise stirs up emotions for many of the couples, leaving Jackie in tears and bringing Quad and Greg's marital issues to a head.

Quad and Toya face off with Mariah in the courtroom, lending their support to Reco Chappelle, as he disputes Mariah's restraining order. Meanwhile, Jackie is visited by her stepdaughter Kursten, who reveals something surprising. Later, Mariah decides to extend a peace offering to all the ladies by inviting them to the launch of her new business venture. Then, after all her hard work, Lisa Nicole unveils her design collection to Atlanta and the world.

Toya shows off her new extravagant home to Dr. Heavenly who has a lot to say. Meanwhile, Quad is finally ready to launch her puppy couture line with a fabulous fashion show. Everyone, except Mariah, shows up to support Quad. Will Quad succeed at getting the investors she needs to help her company take off?

Host Andy Cohen reflects on some of the season's most talked about moments, as the MDs and Mrs. MDs come together in part one of the explosive Married to Medicine reunion. Mariah and Quad finally come face to face to reveal the truth about what really went down between them; Heavenly hears from the ladies on what they really think of her; Simone and Toya's disagreement on stage spills over to backstage, putting the rest of the Reunion in jeopardy. [Part 1 of 2]

The Married to Medicine Reunion continues as host Andy Cohen gets to the bottom of what happened backstage between Simone and Toya. The husbands join to shed their perspective on kids, sex and cheating. Later, Lisa Nicole dishes her grievances with Mariah. After hashing out new and old issues, can the ladies come together as a group again? [Part 2 of 2]

This special looks back at lost footage and never-before-seen cast interviews from Season 2.

The first ladies of medicine are back and busier than ever. Simone and Toya’s friendship is on the fence, but when Toya decides to throw a Halloween party to show off her new house, her husband Eugene insists she invites Simone to bury the hatchet. Quad is full speed ahead with her puppy couture line but when Quad learns Lisa Nicole ran a background check on her for “business” reasons, the two have a fall out. Meanwhile, Dr. Jackie’s latest endeavor is to test out a lifestyle fitness program on the girls and hopefully everyone is willing to jump on board.

Dr. Simone and Toya are at odds but unlike their wives, husbands Cecil and Eugene are determined to save their friendship by forcing an olive branch into Simone and Toya’s strained relationship. Still reeling over Lisa’s surprise background check, Quad flips the script and hires a private investigator to dig up dirt on Lisa Nicole and her husband Darren. Later, Jackie and her trainer Al ambush the girls with a surprise invite to join her latest fitness venture.

Trying to find the root of her anger, Jackie helps Simone understand how her dad’s past transgressions are still affecting her life. As the ladies gather to celebrate Lisa Nicole and Heavenly's magazine cover, Simone comes face to face with Toya for the first time since their disagreement. Meanwhile, following a successful meeting with the private investigator, Quad receives all the information she needs to finally give Lisa Nicole a taste of her own medicine.

Hoping to move past the background check, Quad calls Lisa Nicole for an in-person meeting in hopes of teaching her a lesson in the art of friendship. Things take an unexpected turn when Quad makes a startling accusation which leaves Lisa Nicole reeling. Meanwhile, Heavenly prepares for a date with her hubby and enlists her daughter, Alaura’s help for some serious fashion guidance. Jackie hits the ground running and kicks off her new fitness program, “Fit Is the New It.” However, it is hard to concentrate on getting fit as word reaches the circle of friends about Quad and Lisa’s unexpected encounter.  

In order to regroup, Quad decides that taking some time away from the ladies is her best option. With fitness her top priority, Jackie goes into drill sergeant mode to snap Simone out of her bad junk food habits. Meanwhile, some of the ladies decide to spend some quality time at a strip club but it’s not all fun and games when Lisa Nicole learns that the establishment is one of her husband’s habitual stomping grounds.   

Still reeling from her visit to the strip club, Lisa confronts her husband in order to discover the truth. In hopes of being a supportive wife, Toya tries to get involved with her husband’s new business venture. Always the ones to inform and enlighten, Simone and Jackie demonstrate safe-sex techniques that embarrass some of the ladies and perks the interest of others. Meanwhile, through laughter and tears, Mariah and Quad try their best to mend their relationship but aren’t sure if they can dive back into their friendship.

Jackie comes up with a creative strategy to whip the girls into shape in the second phase of Fit Is The New It. Meanwhile, an anxious Simone is happy when her sister comes to town to hold her hand through her son’s first date. Wanting to settle the score once and for all, Lisa Nicole meets with her attorney to discuss legal options against Quad, while Quad brings in high-powered attorney Phaedra Parks to weigh in on the matter.

Quad leaves the messy drama of Atlanta behind and jets off to sunny California with Simone and Jill. Meanwhile, Jackie struggles to deal with her ailing father both as a daughter and a doctor. Lisa Nicole celebrates her son’s birthday with a fabulous cooking party but while the bash is in full swing, she drops a bomb that leaves Heavenly and Toya in shock.