Stan is ecstatic--and energetic--when a coworker gives him pills that allow him to stay up all night.

A mold of Francine's vagina is displayed in a museum.

An aspiring inventor leaves the Farm to make a go of it in The Big City.

When Stan enters an essay contest to have his personal hero, President Bush, come over for dinner, he is overcome with joy when the President arrives at his doorstep. However, not everyone in the Smith family shares Stan's excitement. Hayley tries to drill President Bush on the Iraq war, and Steve and Roger attempt to convince him that they've found Osama Bin Laden, but instead get him drunk. Stan tries to save the President from public humiliation, while Hayley revels in his fall from glory.

When Stan catches Steve playing imaginary games with his toys, he decides to take his son down to Mexico to help him become a man. But the trip takes a turn for the worse when Stan and Steve are kidnapped by a drug cartel, and it’s up to Steve to break himself and Stan out of captivity.

When Roger and Francine go wine-tasting, Roger plants a big kiss on Francine in a drunken moment. Francine decides to tell Stan about this incident, but when they sit down to talk, Roger convinces Stan that Francine started it all.

When Stan tries to trick Steve into attending summer camp, things go horribly wrong and Steve ends up in a refugee camp. However, Stan, being the eternal optimist, joins Steve and manages to stage a camp Olympics between the refugees and the rebel faction living across the river.

Stan loses his confidence, and his job, when a car salesman gets the best of him in a negotiation. Meanwhile, Roger and Steve set up a makeshift drive-in to try to get to first base with popular schoolgirls.

It's Roger's 1600th birthday, but the Smiths are too freaked out by Steve's impending puberty to celebrate. So Roger decides to make his own birthday fun.

Roger declares that he was sent to Earth to be "the decider" of humanity's fate, and Stan challenges him on it.

Steve must become the man of the house when Stan re-lives his childhood.

Everyone is separated after the ship explodes: Stan and Francine lose their memories and resort to primitive living on an island; Hayley and Jeff are rescued by the Navy and Jeff decides to enlist; and Roger and Steve try to survive on a lifeboat in the middle of the ocean.

When Langley Falls bans trans fats, Stan and Steve become smugglers. Meanwhile, Klaus gets word that he has received an inheritance but can't collect it because the CIA has turned him into a fish.

Despite Francine's warning, Stan gives Steve a gun for Christmas; Steve accidentally shoots Santa.

A talk show reveals that Francine was the toddler who, famously, was rescued from a well by a firefighter; Francine makes a discovery when she falls down the well on the anniversary of her rescue; Stan and Roger come up with a business idea.

To have a chance with a girl, Steve and Snot must track down a keg of 4Loko.

When Steve gives the family better Christmas gifts than Stan, Stan goes to great lengths to regain his title of "King of Presents."

Stan, Francine and Roger concoct the perfect plan to rob a bank but agree never to do it. Peace reigns.

As Stan continues to dominate the household, Francine finds herself idolizing a group of women who seem to have it all. She tries to impress them and even lies in order to gain acceptance into their group, until she realizes they aren't as perfect as they seem. Meanwhile, loyalties are tested when Stan gets a new best friend.

When Roger helps Steve see that his father isn't as smart as he always believed, the power-hungry pair set their sights on fame and fortune in New York City. It doesn't take long for Roger to lose everything on Wall Street, and Steve contemplates prostitution after Jon Stewart shoots down his comedy routine. Meanwhile, the rest of the family is certain that the two have just run away to the tree house, so when it explodes in a lightning storm, they are devastated, but console themselves with Steve's college fund.

Roger is forced to confront himself after a series of accidents. Klaus and Jeff bond.

When Steve brings home a permission slip to take sex ed at school, Stan flips out and demands to teach it himself. However, after Stan unrealistically explains the birds and the bees to Steve, he gets into an accident that causes him to take matters into his own hands. Meanwhile, Roger becomes a bartender in hopes of making something of himself.

When Stan goes to Atlantic City for a bachelor party and is shunned by his so-called best friend, Roger steps in and becomes Stan's new sidekick. Their friendship goes to a whole new level, but when they return home and face Francine, Stan realizes that what happens in Atlantic City doesn't necessarily stay there. Meanwhile, Hayley and Steve team up to break up a good-looking couple.

After Stan discovers that Francine has a secret sex garden, he feels like their marriage may be crumbling. Looking to rekindle their romance, Francine asks for a divorce so that Stan can experience life as a bachelor again, and both learn a valuable lesson in love. Meanwhile, addicted to an energy drink, Steve finds himself panhandling in the streets to support his new habit.

When Stan admits that his heroes include the 1980 U.S. Olympic hockey team, Roger confesses that he played on the team; Reginald tries to win over Hayley by taking her to a concert.