8.3/103,236 votes#1 - A Hard Day's Night
Season 1 Episode 1 - Aired 3/27/2005
Meet Meredith Grey. Daughter of famous surgeon Ellis Grey and currently recovering from a one-night stand. She shoos away her evening's companion, saying she'll be late for her first day of work. She is a first year intern at Seattle Grace Hospital and is working alongside some colorful characters. Cristina Yang is a highly competitive Stanford graduate who befriends Meredith. George O'Malley is a quirky warm hearted man who learns a lesson or two on his first day. Izzie Stevens is a former model who doesn't get any special treatment on her first day. And Alex Karev is an arrogant jerk who misdiagnoses a patient on his first shift. Overseeing them is Miranda Bailey, (not-so-) affectionately dubbed 'The Nazi'. Meredith also gets a surprise when she realizes that her friend from the night before is a co-worker, and even worse, her boss.
Director: Peter Horton
Writer: Shonda Rhimes
8.1/102,222 votes#2 - The First Cut is the Deepest
Season 1 Episode 2 - Aired 4/3/2005
The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile Meredith puts her career on the line to save a newborn in the hospital nursery, and the other interns learn that it takes more than just medical knowledge to be good at their jobs.
Director: Peter Horton
Writer: Shonda Rhimes
8.0/102,053 votes#3 - Winning a Battle, Losing the War
Season 1 Episode 3 - Aired 4/10/2005
A bike race injures several pedestrians as well as well as participants. One pedestrian is left brain dead. Christina and Issie wish to use his organs for organ donation but with Christina's detachment and Issie's ever hopeful attitude that the man will recover, they will find the organ harvesting process an emotional one. Preston faces feelings of his dislike of organ harvesting - as a surgeon, he likes saving lives; harvesting organs doesn't save the person's life. George deals with Mac, a friend of the chief, who won't stop flirting with him. He is in need of a new liver. Meredith is fed up with Alex showing off as she continues trying to push Derek away. She also is reaching the limits of Issie's sunshine and George's politeness as she goes on living with them. Then there is their desire to see Meredith's mother's medical tapes. Getting through the day, Meredith realizes the keys to winning the race.
Director: Tony Goldwyn
Writer: Shonda Rhimes
8.0/101,936 votes#4 - No Man's Land
Season 1 Episode 4 - Aired 4/17/2005
While George is feeling a little less masculine because of the way Izzie and Meredith have been treating him (like a sister), Izzie is assigned to a patient about to loose all of his masculinity. Cristina, true to her competitive spirit, shows up early and assigns herself to an ill woman, who happens to have been Meredith's moms scrub nurse. Alex, meanwhile, is busying himself copying and pasting pictures of Izzie's racy magazine spread all over the interns' locker room. And while Meredith is trying to cope with her mother's Alzheimer's, Derek treats a patient who has managed to get nails stuck in his head.
Director: Adam Davidson
Writer: James D. Parriott
8.0/101,872 votes#5 - Shake Your Groove Thing
Season 1 Episode 5 - Aired 4/24/2005
Meredith realizes that she must take on a lot more responsibility when she is told that her mother needs to sign over all of her assets to her. As Izzie prepares to have a party for her boyfriend Hank (the scale of which is unknown to Meredith), Meredith has her first heart surgery. During the surgery she fears that she has fallen asleep and damaged the patient's heart. Meanwhile, Cristina and Burke hit it off. At the party, Meredith and Derek get caught together by Dr. Bailey.
Director: John David Coles
Writer: Ann Lewis Hamilton
8.1/101,808 votes#6 - If Tomorrow Never Comes
Season 1 Episode 6 - Aired 5/1/2005
Izzie tries to get George to find the courage to ask Meredith out. All of the interns are in awe when a woman comes in with a record breaking tumor, but it is so far advanced that the woman's prognosis is not good. Now that Bailey knows about Meredith and Derek's affair, their jobs are in jeopardy, and she advises Meredith to end it. Meanwhile, Cristina and Burke's secret relationship is also getting more complicated...
Director: Scott Brazil
Writer: Krista Vernoff
8.1/101,782 votes#7 - The Self-Destruct Button
Season 1 Episode 7 - Aired 5/8/2005
Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former competitor who now finds honor in self-mutilation, Izzie has to deal with a patient who won't let go of his girlfriend - literally, and Cristina seems to be battling a case of the flu.
Director: Darnell Martin
Writer: Kip Koenig
8.0/101,762 votes#8 - Save Me
Season 1 Episode 8 - Aired 5/15/2005
Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.
Director: Sarah Pia Anderson
Writer: Mimi Schmir
8.6/101,993 votes#9 - Who's Zoomin' Who?
Season 1 Episode 9 - Aired 5/22/2005
A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his own medical concerns. Izzie and Cristina worry about a patient's wife and daughter who can't agree on his care. Burke treats his college buddy Bill, whose medical diagnosis raises some questions regarding his wife's actions. Then just as Meredith and Derek grow more intimate, a surprise is revealed.
Director: Wendey Stanzler
Writer: Gabrielle Stanton, Harry Werksman
The Best Episodes of Grey's Anatomy Season 1
Every episode of Grey's Anatomy Season 1 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 1!
Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.
Genre:Drama
Network:ABC
Season 1 Ratings Summary
"A Hard Day's Night" is the best rated episode of "Grey's Anatomy" season 1. It scored 8.3/10 based on 3236 votes. Directed by Peter Horton and written by Shonda Rhimes, it aired on 3/27/2005. This episode is rated 0.2 points higher than the second-best, "The First Cut is the Deepest".