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The Best Episodes of Grey's Anatomy Season 22

Every episode of Grey's Anatomy Season 22 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 22!

Binge this in 10h 54m•Peaking at 8.5/10

Follows the personal and professional lives of a group of doctors at Seattle's Grey Sloan Memorial Hospital.

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Episode Rankings

  1. #1 Fan Favorite
    Grey's Anatomy Season 22 Episode 1 - Only the Strong Survive
    8.4/10(11 votes)

    #1 - Only the Strong Survive

    S22:E1

    After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

    Director:Debbie Allen
    Writer:Meg Marinis

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  2. Grey's Anatomy Season 22 Episode 2 - We Built This City
    8.5/10(6 votes)

    #2 - We Built This City

    S22:E2

    The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

    Director:Kevin McKidd
    Writer:Zoanne Clack

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  3. Grey's Anatomy Season 22 Episode 3 - Between Two Lungs
    7.8/10(8 votes)

    #3 - Between Two Lungs

    S22:E3

    A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

    Director:Debbie Allen
    Writer:Sandra Hamada

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  4. Grey's Anatomy Season 22 Episode 4 - Goodbye Horses
    7.3/10(7 votes)

    #4 - Goodbye Horses

    S22:E4

    The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

    Director:Sammi Cannold
    Writer:Jase Miles-Perez

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  5. Grey's Anatomy Season 22 Episode 5 - Sometimes I Feel Like a Motherless Child
    8.3/10(6 votes)

    #5 - Sometimes I Feel Like a Motherless Child

    S22:E5

    Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

    Director:Bille Woodruff
    Writer:Jess Righthand

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  6. Grey's Anatomy Season 22 Episode 6 - When I Crash
    8.5/10(6 votes)

    #6 - When I Crash

    S22:E6

    Grey Sloan takes in patients following a catastrophic bus accident. Teddy and Owen have an awkward encounter, and Richard tests Bailey's patience.

    Director:Phylicia Rashād
    Writer:Michelle Lirtzman

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  7. Grey's Anatomy Season 22 Episode 7 - Skyfall
    8.0/10(5 votes)

    #7 - Skyfall

    S22:E7

    Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

    Director:Allison Liddi-Brown
    Writer:Carol Brown

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  8. Grey's Anatomy Season 22 Episode 8 - Heavy on Me
    8.2/10(5 votes)

    #8 - Heavy on Me

    S22:E8

    Bailey and Owen join forces to save a tumor patient, while Richard faces an internal battle. Meanwhile, Jules struggles with her feelings for Winston.

    Director:Lisa Leone
    Writer:Tameson Duffy

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  9. Grey's Anatomy Season 22 Episode 9 - Fortunate Son
    8.4/10(5 votes)

    #9 - Fortunate Son

    S22:E9

    Richard continues to navigate his health. Meanwhile, Meredith and Nick are visited by Nick's estranged sister from Boston.

    Director:Kim Raver
    Writer:Julie Wong

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  10. Grey's Anatomy Season 22 Episode 10 - Strip That Down
    7.2/10(5 votes)

    #10 - Strip That Down

    S22:E10

    Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition. Bailey joins Owen and Blue on a paramedic ride-along.

    Director:Kevin McKidd
    Writer:Park Jin-Woo

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  11. Grey's Anatomy Season 22 Episode 11 - (If You Want It) Do It Yourself
    7.6/10(5 votes)

    #11 - (If You Want It) Do It Yourself

    S22:E11

    Teddy and Winston clash over a case, while Owen and Jules treat a urologist. Lucas struggles with prioritizing patients.

    Director:Linda Klein
    Writer:Scott D. Brown

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  12. Grey's Anatomy Season 22 Episode 12 - Get Lucky
    7.0/10(4 votes)

    #12 - Get Lucky

    S22:E12

    Tensions rise as Teddy and Winston take on a complex procedure, while Kavita and Ben try and impress the new plastics attending. Jo and Link leave the babies with a nanny for the first time.

    Director:Chandra Wilson
    Writer:Jess Righthand

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  13. Grey's Anatomy Season 22 Episode 13 - Love the Way You Lie
    7.5/10(2 votes)

    #13 - Love the Way You Lie

    S22:E13

    Richard tackles a shocking case on his first day back, while Kavita and Jules prepare for a high-stakes presentation. Bailey must have a difficult conversation with a beloved patient, and Jo works to baby-proof the loft.

    Director:Allison Liddi-Brown
    Writer:Sophia Arnao

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  14. Grey's Anatomy Season 22 Episode 14 - Wrecking Ball
    7.0/10(2 votes)

    #14 - Wrecking Ball

    S22:E14

    A couple lands in the hospital with life-altering injuries after a wrecking ball destroys their home. Lucas and Simone struggle to support a young, terminally ill patient, and Richard hosts a prostate screening event.

    Director:Kevin McKidd
    Writer:Michelle Lirtzman

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  15. Grey's Anatomy Season 22 Episode 15 - Take Me to the River
    7.0/10(1 votes)

    #15 - Take Me to the River

    S22:E15

    Bailey and Blue are forced to confront the emotional costs of experimental care. Meanwhile, Owen, Teddy, Simone and Dani help out at a busy rural hospital, and Richard attempts to spread information about early prostate screenings to the community.

    Director:Bille Woodruff
    Writer:Jase Miles-Perez

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Season 22 Ratings Summary

"Only the Strong Survive" is the best rated episode of "Grey's Anatomy" season 22. It scored 8.4/10 based on 11 votes. Directed by Debbie Allen and written by Meg Marinis, it aired on 10/9/2025. This episode is rated 0.1 points higher than the second-best, "We Built This City".