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The Best Episodes of Grey's Anatomy Season 22

Every episode of Grey's Anatomy Season 22 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 22!

Binge this in 4h 21m•Peaking at 8.2/10

Follows the personal and professional lives of a group of doctors at Seattle's Grey Sloan Memorial Hospital.

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Episode Rankings

  1. #1 Fan Favorite
    Grey's Anatomy Season 22 Episode 1 - Only the Strong Survive
    8.1/10(311 votes)

    #1 - Only the Strong Survive

    S22:E1

    After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

    Director:Debbie Allen
    Writer:Meg Marinis

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  2. Grey's Anatomy Season 22 Episode 2 - We Built This City
    7.4/10(221 votes)

    #2 - We Built This City

    S22:E2

    The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

    Director:Kevin McKidd
    Writer:Zoanne Clack

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  3. Grey's Anatomy Season 22 Episode 3 - Between Two Lungs
    7.3/10(200 votes)

    #3 - Between Two Lungs

    S22:E3

    A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

    Director:Debbie Allen
    Writer:Sandra Hamada

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  4. Grey's Anatomy Season 22 Episode 4 - Goodbye Horses
    7.3/10(175 votes)

    #4 - Goodbye Horses

    S22:E4

    The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

    Director:Sammi Cannold
    Writer:Jase Miles-Perez

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  5. Grey's Anatomy Season 22 Episode 5 - Sometimes I Feel Like a Motherless Child
    7.7/10(175 votes)

    #5 - Sometimes I Feel Like a Motherless Child

    S22:E5

    Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

    Director:Bille Woodruff
    Writer:Jess Righthand

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  6. Grey's Anatomy Season 22 Episode 6 - When I Crash
    7.9/10(162 votes)

    #6 - When I Crash

    S22:E6

    Grey Sloan takes in patients following a catastrophic bus accident. Teddy and Owen have an awkward encounter, and Richard tests Bailey's patience.

    Director:Phylicia Rashād
    Writer:Michelle Lirtzman

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  7. Grey's Anatomy Season 22 Episode 7 - Skyfall
    8.2/10(38 votes)

    #7 - Skyfall

    S22:E7

    Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

    Director:Unknown
    Writer:Unknown

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Season 22 Ratings Summary

"Only the Strong Survive" is the best rated episode of "Grey's Anatomy" season 22. It scored 8.1/10 based on 311 votes. Directed by Debbie Allen and written by Meg Marinis, it aired on 10/9/2025. This episode is rated 0.7 points higher than the second-best, "We Built This City".