Grey's Anatomy backdrop
Drama
Grey's Anatomy poster

The Best Episodes of Grey's Anatomy Season 22

Every episode of Grey's Anatomy Season 22 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 22!

The Best Episodes of Grey's Anatomy Season 22

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.
  1. Background image for Only the Strong Survive
    7.2/10(5 votes)

    #1 - Only the Strong Survive

    S22:E1

    After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

    Director:Debbie Allen
    0 Comments

    Be first to comment!

    Start
    !

    Be the first to comment!

  2. Background image for We Built This City
    7.7/10(3 votes)

    #2 - We Built This City

    S22:E2

    The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

    Director:Kevin McKidd
    0 Comments

    Be first to comment!

    Start
    !

    Be the first to comment!

  3. Background image for Between Two Lungs
    10.0/10(1 votes)

    #3 - Between Two Lungs

    S22:E3

    A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

    0 Comments

    Be first to comment!

    Start
    !

    Be the first to comment!

  4. Background image for Goodbye Horses
    NaN/10(0 votes)

    #4 - Goodbye Horses

    S22:E4

    The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

    0 Comments

    Be first to comment!

    Start
    !

    Be the first to comment!

  5. Background image for Sometimes I Feel Like a Motherless Child
    NaN/10(0 votes)

    #5 - Sometimes I Feel Like a Motherless Child

    S22:E5

    Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

    Director:Unknown
    Writer:Unknown
    0 Comments

    Be first to comment!

    Start
    !

    Be the first to comment!

Season 22 Ratings Summary

"Only the Strong Survive" is the best rated episode of "Grey's Anatomy" season 22. It scored 7.2/10 based on 5 votes. Directed by Debbie Allen and written by Meg Marinis, it aired on 10/9/2025. This episode is rated 0.5 points higher than the second-best, "We Built This City".