8.0/101,497 votes#1 - A Change Is Gonna Come
Season 4 Episode 1 - Aired 9/27/2007
Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her.
Director: Michael Grossman, Rob Corn
Writer: Shonda Rhimes
7.8/101,297 votes#2 - Love/Addiction
Season 4 Episode 2 - Aired 10/4/2007
A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up to deal with what her son left behind. Lexie tries to talk to Meredith. Callie is overwhelmed by her new position while Bailey is searching for things to do.
Director: James Frawley
Writer: Debora Cahn
8.0/101,319 votes#3 - Let the Truth Sting
Season 4 Episode 3 - Aired 10/11/2007
The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is trying to deal with his guilt about having sex with Izzie.
Director: Daniel Minahan
Writer: Mark Wilding
7.9/101,347 votes#4 - The Heart of the Matter
Season 4 Episode 4 - Aired 10/18/2007
A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery for an injury he sustained while playing the game. Another patient's, named Courtney, finds out that her cancer is back.
Director: Randall Zisk
Writer: Allan Heinberg
7.9/101,317 votes#5 - Haunt You Every Day
Season 4 Episode 5 - Aired 10/25/2007
It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what most of the doctors believe is an unnecessary surgery. One of the patients is in the hospital because they tried to carve a pumpkin in an unconventional manner.
Director: Bethany Rooney
Writer: Krista Vernoff
7.8/101,258 votes#6 - Kung Fu Fighting
Season 4 Episode 6 - Aired 11/1/2007
A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them convinces an intern to take their place.
Director: Tom Verica
Writer: Stacy McKee
7.8/101,295 votes#7 - Physical Attraction, Chemical Reaction
Season 4 Episode 7 - Aired 11/8/2007
Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith can barely handle it with Lexie anymore.
Director: Jeff Melman
Writer: Joan Rater
7.9/101,333 votes#8 - Forever Young
Season 4 Episode 8 - Aired 11/15/2007
There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her at the hospital.
Director: Tom Verica, Rob Corn
Writer: Mark Wilding
8.5/101,478 votes#9 - Crash Into Me (1)
Season 4 Episode 9 - Aired 11/22/2007
An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.
Director: Michael Grossman
Writer: Shonda Rhimes, Krista Vernoff
8.4/101,405 votes#10 - Crash Into Me (2)
Season 4 Episode 10 - Aired 12/6/2007
Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.
Director: Jessica Yu
Writer: Shonda Rhimes, Krista Vernoff
7.9/101,309 votes#11 - Lay Your Hands on Me
Season 4 Episode 11 - Aired 1/10/2008
George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in her. Alex treats a faith healer.
Director: John Terlesky
Writer: Allan Heinberg
8.0/101,264 votes#12 - Where The Wild Things Are
Season 4 Episode 12 - Aired 4/24/2008
Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.
Director: Rob Corn
Writer: Zoanne Clack
8.1/101,279 votes#13 - Piece of My Heart
Season 4 Episode 13 - Aired 5/1/2008
Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.
Director: Mark Tinker
Writer: Stacy McKee
8.0/101,470 votes#14 - The Becoming
Season 4 Episode 14 - Aired 5/8/2008
The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affected by Burke's career developments.
Director: Julie Anne Robinson
Writer: Joan Rater
8.0/101,322 votes#15 - Losing My Mind
Season 4 Episode 15 - Aired 5/15/2008
Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Christina continues to act strangely.
Director: James Frawley
Writer: Debora Cahn
8.6/101,676 votes#16 - Freedom (1)
Season 4 Episode 16 - Aired 5/22/2008
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
Director: Rob Corn
Writer: Shonda Rhimes
8.8/101,369 votes#17 - Freedom (2)
Season 4 Episode 17 - Aired 5/22/2008
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
Director: Rob Corn
Writer: Shonda Rhimes
The Best Episodes of Grey's Anatomy Season 4
Every episode of Grey's Anatomy Season 4 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 4!
Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.
Genre:Drama
Network:ABC
Season 4 Ratings Summary
"A Change Is Gonna Come" is the best rated episode of "Grey's Anatomy" season 4. It scored 8/10 based on 1497 votes. Directed by Michael Grossman, Rob Corn and written by Shonda Rhimes, it aired on 9/27/2007. This episode is rated 0.2 points higher than the second-best, "Love/Addiction".