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Grey's Anatomy S5E22 — What a Difference a Day Makes
9.2
Grey's Anatomy•Season 5•Episode 22

What a Difference a Day Makes

9.2/10 · 2,182 votesMay 7, 200943 min

Ranked #2 of 24 in Season 5•+0.8 vs season avg

Discussion

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing

Directed byRob Corn
Written byShonda Rhimes
Previous episodeE21 · No Good at Saying Sorry (One More Chance)Next episodeE23 · Here's to Future Days
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Cast12

Ellen Pompeo

Ellen Pompeo

Meredith Grey

Chandra Wilson

Chandra Wilson

Miranda Bailey

Sandra Oh

Sandra Oh

Cristina Yang

Justin Chambers

Justin Chambers

Alex Karev

James Pickens Jr.

James Pickens Jr.

Richard Webber

Patrick Dempsey

Patrick Dempsey

Derek Shepherd

Kevin McKidd

Kevin McKidd

Owen Hunt

Katherine Heigl

Katherine Heigl

Izzie Stevens

Sara Ramirez

Sara Ramirez

Callie Torres

Eric Dane

Eric Dane

Mark Sloan

Chyler Leigh

Chyler Leigh

Lexie Grey

T. R. Knight

T. R. Knight

George O'Malley

Crew2

Shonda Rhimes

Shonda Rhimes

Writer

R

Rob Corn

Director

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Episode Summary

"What a Difference a Day Makes" is episode 22 of Grey's Anatomy season 5. It scored 9.2/10 from 2,182 votes, ranking #2 of 24 episodes this season (season average 8.4). Directed by Rob Corn and written by Shonda Rhimes, it aired on May 7, 2009.

Next: E23 · Here's to Future DaysBest of Season 5